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Article

Identification of ALK Rearrangements in Malignant Peritoneal Mesothelioma.

JAMA oncology - 1 Feb 2018

Hung Yin P, Dong Fei, Watkins Jaclyn C, Nardi Valentina, Bueno Raphael, Dal Cin Paola, Godleski John J, Crum Christopher P, Chirieac Lucian R

Abstract excerpt

IMPORTANCE: Malignant peritoneal mesothelioma is a rare, aggressive tumor arising from the peritoneal lining, induced by asbestos, therapeutic radiation, or germline mutations. Nevertheless, the molecular features remain largely unknown. OBJECTIVE: To investigate anaplastic lymphoma kinase (ALK) rearrangements in a large series of peritoneal mesothelioma and characterize the mutational landscape of these tumors....

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Topics

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Share to Anaplastic Lymphoma Kinase
Share to High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Mesothelioma

Share to Mesothelioma, Malignant

Share to Oncogene Proteins, Fusion

Share to Peritoneal Neoplasms

Share to Translocation, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 28910456
DOI: 10.1001/jamaoncol.2017.2918
PMCID: PMC5838580

Genes

ALK
BAP1
SETD2
STRN
TPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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