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Article

Pediatric Mesothelioma With ALK Fusions: A Molecular and Pathologic Study of 5 Cases.

The American journal of surgical pathology - 1 May 2021

Argani Pedram, Lian Derrick W Q, Agaimy Abbas, Metzler Markus, Wobker Sara E, Matoso Andres, Epstein Jonathan I, Sung Yun-Shao, Zhang Lei, Antonescu Cristina R

Abstract excerpt

Pediatric mesotheliomas are rare and their pathogenesis remains undefined. In this study, we report 5 cases of malignant mesothelioma in children, characterized by fusions involving the anaplastic lymphoma kinase (ALK) gene. Four cases occurred in females involving the abdominal cavity and were characterized by a pure epithelioid morphology. The fifth arose in the tunica vaginalis of a 15-year-old male and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33399341
DOI: 10.1097/PAS.0000000000001656
PMCID: PMC8035308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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