Article
Molecular and Immunohistochemical Testing in Mesothelioma and Other Mesothelial Lesions.
Archives of pathology & laboratory medicine - 1 May 2024
Hung Yin P, Chirieac Lucian R
Abstract excerpt
CONTEXT.—: Molecular testing has increasingly been utilized in the evaluation of mesothelioma. Diffuse mesothelioma comprises multiple distinct genetic subgroups. While most diffuse mesotheliomas lack oncogenic kinase mutations and instead harbor alterations involving tumor suppressors and chromatin regulators, a minor subset of tumors is characterized by uncommon alterations such as germline mutations, genomic...
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