Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Malignant cells from pleural fluids in malignant mesothelioma patients reveal novel mutations.

Lung cancer (Amsterdam, Netherlands) - 1 May 2018

Sneddon Sophie, Dick Ian, Lee Y C Gary, Musk A W Bill, Patch Ann-Marie, Pearson John V, Waddell Nicola, Allcock Richard J N, Holt Robert A, Robinson Bruce W S, Creaney Jenette

Abstract excerpt

OBJECTIVES: Malignant mesothelioma (MM) is an asbestos related tumour affecting cells of serosal cavities. More than 70% of MM patients develop pleural effusions which contain tumour cells, representing a readily accessible source of malignant cells for genetic analysis. Although common somatic mutations and losses have been identified in solid MM tumours, the characterization of tumour cells within pleural...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asbestos
Share to Cyclin-Dependent Kinase Inhibitor p16

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Environmental Exposure

Share to Mesothelioma

Share to Mesothelioma, Malignant

Share to Neurofibromin 2

Share to Pleural Effusion, Malignant

Share to Ubiquitin Thiolesterase

Source

Identifiers

PMID: 29656754
DOI: 10.1016/j.lungcan.2018.03.009

Genes

BAP1
FGFR3
LATS2
TRAF7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Malignant cells from pleural fluids in malignant mesothelioma patients reveal novel mutations.PMID 29656754Read ↗

Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations.Semantic proximity Read ↗

BAP1 mutation is a frequent somatic event in peritoneal malignant mesothelioma.Semantic proximity Read ↗

Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma.Semantic proximity Read ↗

Progress and challenges in Mesothelioma: From bench to bedside.Semantic proximity Read ↗

Genomics and Functional Genomics of Malignant Pleural MesotheliomaSemantic proximity Read ↗

Whole exome sequencing of an asbestos-induced wild-type murine model of malignant mesothelioma.Semantic proximity Read ↗

Genomics and Epigenetics of Malignant MesotheliomaSemantic proximity Read ↗

Whole exome and targeted deep sequencing identify genome-wide allelic loss and frequent SETDB1 mutations in malignant pleural mesotheliomas.Semantic proximity Read ↗

A molecular phenotypic map of Malignant Pleural MesotheliomaSemantic proximity Read ↗

Molecular pathogenesis of malignant mesotheliomaSemantic proximity Read ↗

Whole-genome sequencing of human malignant mesothelioma tumours and cell linesSemantic proximity Read ↗

Personalized Oncogenomics: Clinical Experience with Malignant Peritoneal Mesothelioma Using Whole Genome SequencingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.