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Article

Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania.

Genome research - 1 Dec 2011

Rogers Matthew B, Hilley James D, Dickens Nicholas J, Wilkes Jon, Bates Paul A, Depledge Daniel P, Harris David, Her Yerim, Herzyk Pawel, Imamura Hideo, Otto Thomas D, Sanders Mandy, Seeger Kathy, Dujardin Jean-Claude, Berriman Matthew, Smith Deborah F, Hertz-Fowler Christiane, Mottram Jeremy C

Abstract excerpt

Leishmania parasites cause a spectrum of clinical pathology in humans ranging from disfiguring cutaneous lesions to fatal visceral leishmaniasis. We have generated a reference genome for Leishmania mexicana and refined the reference genomes for Leishmania major, Leishmania infantum, and Leishmania braziliensis. This has allowed the identification of a remarkably low number of genes or paralog groups (2, 14, 19,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22038252
DOI: 10.1101/gr.122945.111
PMCID: PMC3227102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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