Article
Comparative genomics of Tunisian Leishmania major isolates causing human cutaneous leishmaniasis with contrasting clinical severity.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2017
Ghouila Amel, Guerfali Fatma Z, Atri Chiraz, Bali Aymen, Attia Hanene, Sghaier Rabiaa M, Mkannez Ghada, Dickens Nicholas J, Laouini Dhafer
Abstract excerpt
Zoonotic cutaneous leishmaniasis caused by Leishmania (L.) major parasites affects urban and suburban areas in the center and south of Tunisia where the disease is endemo-epidemic. Several cases were reported in human patients for which infection due to L. major induced lesions with a broad range of severity. However, very little is known about the mechanisms underlying this diversity. Our hypothesis is that...
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