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Article

BRCA2 carriers with male breast cancer show elevated tumour methylation.

BMC cancer - 11 Sept 2017

Deb Siddhartha, Gorringe Kylie L, Pang Jia-Min B, Byrne David J, Takano Elena A, Dobrovic Alexander, Fox Stephen B

Abstract excerpt

BACKGROUND: Male breast cancer (MBC) represents a poorly characterised group of tumours, the management of which is largely based on practices established for female breast cancer. However, recent studies demonstrate biological and molecular differences likely to impact on tumour behaviour and therefore patient outcome. The aim of this study was to investigate methylation of a panel of commonly methylated breast...

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Topics

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Share to BRCA1 Protein
Share to BRCA2 Protein
Share to Breast Neoplasms, Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Heterozygote

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Share to Twist-Related Protein 1

Source

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Identifiers

PMID: 28893223
DOI: 10.1186/s12885-017-3632-7
PMCID: PMC5594583

Genes

BRCA2
RUNX3
TWIST1
WIF1
APC
BRCA1
CDH1
FOXC1
GSTP1
MAL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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