Article
Clinicopathological features, genetic alterations, and BRCA1 promoter methylation in Japanese male patients with breast cancer.
Breast cancer research and treatment - 1 Feb 2023
Shimomura Akihiko, Yoshida Masayuki, Kubo Takashi, Yamashita Satoshi, Noguchi Emi, Nagayama Aiko, Hanamura Toru, Okazaki Miki, Mukohara Toru, Tsuruga Asako, Tanaka Kiyo, Kawamura Yukino, Higuchi Toru, Takahashi Yoko, Kurozumi Sasagu, Hayashida Tetsu, Ichikawa Hitoshi, Ushijima Toshikazu, Suto Akihiko
Abstract excerpt
PURPOSE: Male breast cancer (MBC) is a rare cancer accounting for only 1% of all male cancers and is, therefore, poorly studied. We aimed to characterize the subtypes of MBC in Japanese patients based on genetic profiling, the presence of tumor-infiltrating cells, and the expression of immunohistochemical markers. METHODS: This retrospective study included 103 patients with MBC diagnosed between January 2009 and...
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