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Article

Promoter hypermethylation in male breast cancer: analysis by multiplex ligation-dependent probe amplification

5 Jul 2012

Abstract excerpt

INTRODUCTION: Epigenetic events are, along with genetic alteration, important in the development and progression of cancer. Promoter hypermethylation causes gene silencing and is thought to be an early event in carcinogenesis. The role of promoter hypermethylation in male breast cancer has not yet been studied. METHODS: In a group of 108 male breast cancers, the methylation status of 25 genes was studied using...

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PMID: 22765268
DOI: 10.1186/bcr3220

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