Article
Variants in the vitamin D pathway, serum levels of vitamin D, and estrogen receptor negative breast cancer among African-American women: a case-control study.
Breast cancer research : BCR - 4 Apr 2012
Yao Song, Zirpoli Gary, Bovbjerg Dana H, Jandorf Lina, Hong Chi Chen, Zhao Hua, Sucheston Lara E, Tang Li, Roberts Michelle, Ciupak Gregory, Davis Warren, Hwang Helena, Johnson Candace S, Trump Donald L, McCann Susan E, Ademuyiwa Foluso, Pawlish Karen S, Bandera Elisa V, Ambrosone Christine B
Abstract excerpt
INTRODUCTION: American women of African ancestry (AA) are more likely than European Americans (EA) to have estrogen receptor (ER)-negative breast cancer. 25-hydroxyvitamin D (25OHD) is low in AAs, and was associated with ER-negative tumors in EAs. We hypothesized that racial differences in 25OHD levels, as well as in inherited genetic variations, may contribute, in part, to the differences in tumor...
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