Article
Common vitamin D pathway gene variants reveal contrasting effects on serum vitamin D levels in African Americans and European Americans.
Human genetics - 1 Nov 2014
Batai Ken, Murphy Adam B, Shah Ebony, Ruden Maria, Newsome Jennifer, Agate Sara, Dixon Michael A, Chen Hua Yun, Deane Leslie A, Hollowell Courtney M P, Ahaghotu Chiledum, Kittles Rick A
Abstract excerpt
Vitamin D deficiency is more common among African Americans (AAs) than among European Americans (EAs), and epidemiologic evidence links vitamin D status to many health outcomes. Two genome-wide association studies (GWAS) in European populations identified vitamin D pathway gene single-nucleotide polymorphisms (SNPs) associated with serum vitamin D [25(OH)D] levels, but a few of these SNPs have been replicated in...
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