Article
Genetic Polymorphisms in Vitamin D Metabolism and Signaling Genes and Risk of Breast Cancer: A Nested Case-Control Study.
PloS one - 1 Jan 2015
Clendenen Tess V, Ge Wenzhen, Koenig Karen L, Axelsson Tomas, Liu Mengling, Afanasyeva Yelena, Andersson Anne, Arslan Alan A, Chen Yu, Hallmans Göran, Lenner Per, Kirchhoff Tomas, Lundin Eva, Shore Roy E, Sund Malin, Zeleniuch-Jacquotte Anne
Abstract excerpt
Genetic polymorphisms in vitamin D metabolism and signaling genes have been inconsistently associated with risk of breast cancer, though few studies have examined SNPs in vitamin D-related genes other than the vitamin D receptor (VDR) gene and particularly have not examined the association with the retinoid X receptor alpha (RXRA) gene which may be a key vitamin D pathway gene. We conducted a nested case-control...
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