Article
Balancing anti-inflammatory and anti-oxidant responses in murine bone marrow derived macrophages.
PloS one - 1 Jan 2017
Nitkin Christopher R, Bonfield Tracey L
Abstract excerpt
RATIONALE: The underlying pathophysiology of bronchopulmonary dysplasia includes a macrophage-mediated host response orchestrated by anti-inflammatory peroxisome proliferator-activated receptor gamma (PPARγ) and anti-oxidant nuclear factor (erythroid-derived 2)-like 2 (Nrf2). These have not yet been studied in combination. This study tested the hypothesis that combined inflammatory and oxidative stressors would...
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