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Article

Deficits in lung alveolarization and function after systemic maternal inflammation and neonatal hyperoxia exposure.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 May 2010

Velten Markus, Heyob Kathryn M, Rogers Lynette K, Welty Stephen E

Abstract excerpt

Systemic maternal inflammation contributes to preterm birth and is associated with development of bronchopulmonary dysplasia (BPD). Infants with BPD exhibit decreased alveolarization, diffuse interstitial fibrosis with thickened alveolar septa, and impaired pulmonary function. We tested the hypothesis that systemic prenatal LPS administration to pregnant mice followed by postnatal hyperoxia exposure is associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20223995
DOI: 10.1152/japplphysiol.01392.2009
PMCID: PMC2867533

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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