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Article

BRCA1 gene: function and deficiency.

International journal of clinical oncology - 1 Feb 2018

Takaoka Miho, Miki Yoshio

Abstract excerpt

The BRCA1 protein, a hereditary breast and ovarian cancer-causing gene product, is known as a multifunctional protein that performs various functions in cells. It is well known, along with BRCA 2, to cause hereditary breast and ovarian cancer, but here we will specifically focus on BRCA1. We introduce the mechanism and the latest report on homologous recombination repair, replication, involvement in checkpoint...

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Share to BRCA1 Protein
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Share to Chromatin Assembly and Disassembly

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair

Share to Genes, BRCA1

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Source

Identifiers

PMID: 28884397
DOI: 10.1007/s10147-017-1182-2

Genes

BRCA1

Provenance

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