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Article

The role of BRCA1 in DNA double-strand repair: past and present.

Experimental cell research - 10 Mar 2013

Caestecker Kevin W, Van de Walle Gerlinde R

Abstract excerpt

The breast cancer type 1 susceptibility protein (BRCA1) is involved in several important cellular pathways, including DNA damage repair, chromatin remodeling and checkpoint activation. The BRCA1 tumor suppression function has been attributed to its role in homologous recombination damage repair. In this review, historical facts concerning BRCA1, together with recent research advances regarding our understanding...

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Source

Identifiers

PMID: 23200932
DOI: 10.1016/j.yexcr.2012.11.013

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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