Article
High Levels of (Un)Switched Memory B Cells Are Associated With Better Outcome in Patients With Advanced Atherosclerotic Disease.
Journal of the American Heart Association - 7 Sept 2017
Meeuwsen John A L, van Duijvenvoorde Amerik, Gohar Aisha, Kozma Maria O, van de Weg Sander M, Gijsberts Crystel M, Haitjema Saskia, Björkbacka Harry, Fredrikson Gunilla N, de Borst Gert J, den Ruijter Hester M, Pasterkamp Gerard, Binder Christoph J, Hoefer Imo E, de Jager Saskia C A
Abstract excerpt
BACKGROUND: Atherosclerosis is an inflammatory lipid disorder and the main underlying pathology of acute ischemic events. Despite a vast amount of data from murine atherosclerosis models, evidence of B-cell involvement in human atherosclerotic disease is limited. We therefore investigated the association of circulating B-cell subtypes with the occurrence of secondary cardiovascular events in advanced...
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