Article
A new approach to chromosome-wide analysis of X-linked markers identifies new associations in Asian and European case-parent triads of orofacial clefts.
PloS one - 1 Jan 2017
Skare Øivind, Gjessing Håkon K, Gjerdevik Miriam, Haaland Øystein A, Romanowska Julia, Lie Rolv T, Jugessur Astanand
Abstract excerpt
BACKGROUND: GWAS discoveries on the X-chromosome are underrepresented in the literature primarily because the analytical tools that have been applied were originally designed for autosomal markers. Our objective here is to employ a new robust and flexible tool for chromosome-wide analysis of X-linked markers in complex traits. Orofacial clefts are good candidates for such analysis because of the consistently...
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