Article
Phenotyping and susceptibility of established porcine cells lines to African Swine Fever Virus infection and viral production.
Scientific reports - 4 Sept 2017
Sánchez Elena G, Riera Elena, Nogal Marisa, Gallardo Carmina, Fernández Paloma, Bello-Morales Raquel, López-Guerrero José Antonio, Chitko-McKown Carol G, Richt Jürgen A, Revilla Yolanda
Abstract excerpt
African swine fever virus (ASFV) is a highly pathogenic, double-stranded DNA virus with a marked tropism for cells of the monocyte-macrophage lineage, affecting swine species and provoking severe economic losses and health threats. In the present study, four established porcine cell lines, IPAM-WT, IPAM-CD163, C∆2+ and WSL, were compared to porcine alveolar macrophage (PAM) in terms of surface marker phenotype,...
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