Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CD163-Expressing Porcine Macrophages Support NADC30-like and NADC34-like PRRSV Infections

16 Sept 2022

Abstract excerpt

Porcine reproductive and respiratory syndrome virus (PRRSV) has a strict cell tropism. In addition to the primary alveolar macrophages, PRRSV is strictly cytotropic to African green monkey kidney cells, such as MARC-145 cells; however, MARC-145 cells are not infected by most NADC30-like and NADC34-like PRRSV strains. The essential scavenger receptor CD163 has been proved to mediate productive infection of PRRSV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to Viral gastroenteritis research and epidemiology
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36146862
DOI: 10.3390/v14092056

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CD163-Expressing Porcine Macrophages Support NADC30-like and NADC34-like PRRSV InfectionsPMID 36146862Read ↗

Porcine alveolar macrophage CD163 abundance is a pivotal switch for porcine reproductive and respiratory syndrome virus infectionSemantic proximity Read ↗

Role of CD163 in PRRSV infectionSemantic proximity Read ↗

Recent Advances in PRRS Virus Receptors and the Targeting of Receptor–Ligand for ControlSemantic proximity Read ↗

Identification of the CD163 Protein Domains Involved in Infection of the Porcine Reproductive and Respiratory Syndrome VirusSemantic proximity Read ↗

Establishment of an Immortalized Porcine Alveolar Macrophage Cell Line That Supports Efficient Replication of Porcine Reproductive and Respiratory Syndrome VirusesSemantic proximity Read ↗

A brief review of CD163 and its role in PRRSV infectionSemantic proximity Read ↗

Pig macrophages with site-specific edited CD163 decrease the susceptibility to infection with porcine reproductive and respiratory syndrome virusSemantic proximity Read ↗

Structural comparison of CD163 SRCR5 from different species sheds some light on its involvement in porcine reproductive and respiratory syndrome virus-2 infection in vitro.Semantic proximity Read ↗

CD163 expression confers susceptibility to porcine reproductive and respiratory syndrome viruses.Semantic proximity Read ↗

The polymorphism analysis of CD169 and CD163 related with the risk of porcine reproductive and respiratory syndrome virus (PRRSV) infection.Semantic proximity Read ↗

The porcine reproductive and respiratory syndrome virus requires trafficking through CD163-positive early endosomes, but not late endosomes, for productive infectionSemantic proximity Read ↗

Porcine Reproductive and Respiratory Syndrome Virus Modulates the Switch of Macrophage Polarization from M1 to M2 by Upregulating MoDC-Released sCD83Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.