Article
Expression of porcine CD163 on monocytes/macrophages correlates with permissiveness to African swine fever infection.
Archives of virology - 1 Dec 2003
Sánchez-Torres C, Gómez-Puertas P, Gómez-del-Moral M, Alonso F, Escribano J M, Ezquerra A, Domínguez J
Abstract excerpt
Monocytes-macrophages, the target cells of African swine fever virus (ASFV) are highly heterogeneous in phenotype and function. In this study, we have investigated the correlation between the phenotype of specific populations of porcine macrophages and their permissiveness to ASFV infection. Bone marrow cells and fresh blood monocytes were less susceptible to in vitro infection by ASFV than more mature cells,...
Topics
- Animals
- Antigens, CD
- Antigens, Differentiation, Myelomonocytic
- Asfarviridae
- Cells, Cultured
- Macrophages
- Monocytes
- Phenotype
- Receptors, Cell Surface
- Swine
- CD163 Antigen
