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African Swine Fever Virus Exhibits Distinct Replication Defects in Different Cell Types

26 Nov 2022

Abstract excerpt

African swine fever virus (ASFV) causes one of the most devastating diseases affecting pigs and wild suids, a worldwide epizootic situation exacerbated in recent years due to the lack of vaccine or effective treatment. ASFV has a restricted cell tropism, and is prone to replicate in porcine monocytes and alveolar macrophages with high efficiency. Here, the replication capabilities of ASFV were examined in swine...

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PMID: 36560646
DOI: 10.3390/v14122642

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