A Spontaneously Occurring African Swine Fever Virus with 11 Gene Deletions Partially Protects Pigs Challenged with the Parental Strain

Abstract excerpt

African swine fever (ASF) is an infectious Suidae disease caused by the ASF virus (ASFV). Adaptation to less susceptible, non-target host cells is one of the most common techniques used to attenuate virulent viruses. However, this may induce many mutations and large-scale rearrangements in the viral genome, resulting in immunostimulatory potential loss of the virus in vivo. This study continuously maintained the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Animal Disease Management and Epidemiology
• Share to Vector-Borne Animal Diseases
• Share to Viral Infections and Immunology Research