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Article

Functional Enterospheres Derived In Vitro from Human Pluripotent Stem Cells.

Stem cell reports - 12 Sept 2017

Nadkarni Rohan R, Abed Soumeya, Cox Brian J, Bhatia Sonam, Lau Jennifer T, Surette Michael G, Draper Jonathan S

Abstract excerpt

Intestinal organoids derived from human pluripotent stem cells (hPSCs) are valuable in vitro research models that enable simplified access to human gastrointestinal tissues. Here, we report the in vitro generation of enterospheres (hEnS) from hPSC-derived gastrointestinal epithelial precursors. hEnS are cystic spheroids with a simple uniform structure composed entirely of intestinal epithelium. hEnS express...

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Bacterial Infections
Cell Lineage
Endoderm
Enterocytes
Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Human Embryonic Stem Cells

Pluripotent Stem Cells

Spheroids, Cellular

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Identifiers

PMID: 28867347
DOI: 10.1016/j.stemcr.2017.07.024
PMCID: PMC5599260

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