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Article

Splicing dysfunction and disease: The case of granulopoiesis.

Seminars in cell & developmental biology - 1 Mar 2018

Keightley Maria-Cristina, Lieschke Graham J

Abstract excerpt

Splicing is a ubiquitous process in eukaryotic cells, long recognised as contributing to diversity of the transcriptome. More specifically, splicing fine-tunes the transcriptome output for highly individual outcomes at different stages of cell development, in specific timeframes, which when perturbed result in significant human diseases. Granulopoiesis provides a particularly well studied example of how splicing...

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PMID: 28866328
DOI: 10.1016/j.semcdb.2017.08.048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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