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Article

Molecular Subtyping of PrPres in Human Sporadic CJD Brain Tissue.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Klug G M, Lewis V, Collins S J

Abstract excerpt

Across the spectrum of sporadic human prion diseases (also known as transmissible spongiform encephalopathies: TSE), there is considerable phenotypic diversity. Cumulative scientific evidence supports that prions, the infectious agents of prion diseases, are constituted predominantly, if not exclusively, by misfolded, typically protease-resistant, disease-associated isoforms of the prion protein (PrPres)....

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Source

Identifiers

PMID: 28861800
DOI: 10.1007/978-1-4939-7244-9_23

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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