Nucleotide sugar transporters of the Golgi apparatus: from basic science to diseases.

doi:10.1021/ar0400239

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Article

Nucleotide sugar transporters of the Golgi apparatus: from basic science to diseases.

Accounts of chemical research - 1 Nov 2006

Caffaro Carolina E, Hirschberg Carlos B

Abstract excerpt

Approximately 80% of secreted and membrane proteins (40% of all proteins) of eukaryotes become covalently linked to sugars in the lumen of the Golgi apparatus, a cellular organelle that is part of the secretory system of all eukaryotes. The sugar donors are mostly nucleoside diphosphate sugars (nucleotide sugars) and must be translocated from the cytosol, their site of synthesis, across the Golgi apparatus...

Topics

Amino Acid Sequence
Animals
Biological Science Disciplines
Biological Transport
Disease
Golgi Apparatus
Humans
Membrane Transport Proteins
Molecular Sequence Data
Mutation
Nucleoside Diphosphate Sugars
Substrate Specificity

Source

Open in PubMed

Identifiers

PMID: 17115720
DOI: 10.1021/ar0400239

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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