Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Moderate levels of pre-therapy drug resistance (PDR) in a generalised epidemic: time for better first-line ART?

AIDS (London, England) - 1 Nov 2017

van Zyl Gert U, Grobbelaar Cornelis J, Claassen Mathilda, Bock Peter, Preiser Wolfgang

Abstract excerpt

BACKGROUND: The WHO-recommended first-line antiretroviral therapy (ART) as a fixed dose combination (FDC) of efavirenz (EFV) and tenofovir disoproxil fumarate (TDF) with lamivudine (3TC) or emtricitabine (FTC) has been preferred in the large scale unprecedented ART roll out in Southern Africa. Models and recent reports suggest that pre-ART HIV drug resistance (PDR) is increasing with high treatment coverage....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Africa, Southern
Share to Anti-Retroviral Agents

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antiretroviral Therapy, Highly Active

Share to Disease Transmission, Infectious

Share to Drug Resistance, Viral

Share to Epidemics

Share to Genotyping Techniques

Share to HIV Infections

Source

Identifiers

PMID: 28857824
DOI: 10.1097/QAD.0000000000001629

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Moderate levels of pre-therapy drug resistance (PDR) in a generalised epidemic: time for better first-line ART?PMID 28857824Read ↗

Moderate Levels of Pre-Treatment HIV-1 Antiretroviral Drug Resistance Detected in the First South African National Survey.Semantic proximity Read ↗

Pre-treatment HIV-1 drug resistance in antiretroviral therapy-naive adults in Eastern Africa: a systematic review and meta-analysis.Semantic proximity Read ↗

Acquired HIV drug resistance mutations on first-line antiretroviral therapy in Southern Africa: Systematic review and Bayesian evidence synthesis.Semantic proximity Read ↗

Pre-Treatment HIV Drug Resistance and Genetic Diversity in Cameroon: Implications for First-Line Regimens.Semantic proximity Read ↗

High level of HIV-1 drug resistance mutations in patients with unsuppressed viral loads in rural northern South AfricaSemantic proximity Read ↗

Moderate-to-High Levels of Pretreatment HIV Drug Resistance in KwaZulu-Natal Province, South AfricaSemantic proximity Read ↗

Acquired HIV drug resistance and virologic monitoring in a HIV hyper-endemic setting in KwaZulu-Natal Province, South AfricaSemantic proximity Read ↗

Temporal trends and transmission dynamics of pre-treatment HIV-1 drug resistance within and between risk groups in Kenya, 1986-2020.Semantic proximity Read ↗

A retrospective descriptive investigation of adult patients receiving third-line antiretroviral therapy in the North West province, South Africa.Semantic proximity Read ↗

Primary drug resistance in South Africa: data from 10 years of surveys.Semantic proximity Read ↗

HIV transmission dynamics and population-wide drug resistance in rural South Africa.Semantic proximity Read ↗

Drug Resistance Mutations in a Population Before Antiretroviral Therapy Initiation in Northern South Africa.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.