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Article

Pre-treatment HIV-1 drug resistance in antiretroviral therapy-naive adults in Eastern Africa: a systematic review and meta-analysis.

The Journal of antimicrobial chemotherapy - 28 Nov 2022

Ntamatungiro Alex J, Kagura Juliana, Weisser Maja, Francis Joel M

Abstract excerpt

BACKGROUND: Pre-treatment HIV drug resistance (PDR) may result in increased risk of virological failure and acquisition of new resistance mutations. With recently increasing ART coverage and periodic modifications of the guidelines for HIV treatment, there is a need for an updated systematic review to assess the levels of the PDR among adults newly initiating ART in Eastern Africa. METHODS: We conducted a...

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PMID: 36225089
DOI: 10.1093/jac/dkac338

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