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Article

Brain-derived neurotrophic factor Val66Met polymorphism and obsessive-compulsive symptoms in Egyptian schizophrenia patients.

Journal of psychiatric research - 1 Jun 2012

Hashim Haytham M, Fawzy Nagy, Fawzi Mohab M, Karam Rehab A

Abstract excerpt

BACKGROUND: Brain-derived neurotrophic factor (BDNF) has been advanced as a candidate gene for schizophrenia. BDNF promote the function and growth of 5-HT neurons in the brain and modulate the synaptic plasticity of DRD3-secreting neurons in the striatum, suggesting involvement of BDNF in the mediation of obsessive-compulsive disorder. OBJECTIVES: To test the hypothesis that the BDNF Val66Met polymorphism...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22521161
DOI: 10.1016/j.jpsychires.2012.03.007

Genes

BDNF
DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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