Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Capsid Engineering of Adenovirus Vectors: Overcoming Early Vector–Host Interactions for Therapy

31 Aug 2017

Abstract excerpt

Adenovirus-based vectors comprise the most frequently used vector type in clinical studies to date. Both intense lab research and insights from the clinical trials reveal the importance of a comprehensive understanding of vector-host interactions. Especially for systemic intravenous adenovirus vector delivery, it is paramount to develop safe and efficacious vectors. Very early vector-host interactions that take...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Viral gastroenteritis research and epidemiology
Share to Viral Infectious Diseases and Gene Expression in Insects
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28854810
DOI: 10.1089/hum.2017.139

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Capsid Engineering of Adenovirus Vectors: Overcoming Early Vector–Host Interactions for TherapyPMID 28854810Read ↗

Genetic and Chemical Capsid Modifications of Adenovirus Vectors to Modulate Vector–Host InteractionsSemantic proximity Read ↗

Capsid and Genome Modification Strategies to Reduce the Immunogenicity of Adenoviral VectorsSemantic proximity Read ↗

The Adenovirus Vector Platform: Novel Insights into Rational Vector Design and Lessons Learned from the COVID-19 VaccineSemantic proximity Read ↗

Adenovirus – a blueprint for gene deliverySemantic proximity Read ↗

Viral vector platforms within the gene therapy landscapeSemantic proximity Read ↗

State‐of‐the‐art human adenovirus vectorology for therapeutic approachesSemantic proximity Read ↗

Evolving Horizons: Adenovirus Vectors’ Timeless Influence on Cancer, Gene Therapy and VaccinesSemantic proximity Read ↗

Advances and Future Challenges in Adenoviral Vector Pharmacology and TargetingSemantic proximity Read ↗

Advancements in the design and scalable production of viral gene transfer vectorsSemantic proximity Read ↗

Adenoviral Gene Therapy Vectors in Clinical Use—Basic Aspects with a Special Reference to Replication-Competent Adenovirus Formation and Its Impact on Clinical SafetySemantic proximity Read ↗

Adeno-associated virus (AAV) capsid engineering in liver-directed gene therapySemantic proximity Read ↗

On the in vivo kinetics of gene delivery vectorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.