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State‐of‐the‐art human adenovirus vectorology for therapeutic approaches

23 Nov 2019

Abstract excerpt

Human adenoviruses (Ads) have long been studied in the basic virology field and are exploited as vectors for gene therapy, vaccination, and oncolytic therapy. Ads are usually mild pathogens, but they can cause severe infections and symptoms in immunocompromised individuals. Ads show a large natural diversity and a broad spectrum of hosts. However, replication-competent and replication-deficient Ad vectors with...

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PMID: 31758807
DOI: 10.1002/1873-3468.13691

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