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Article

Mutagenesis and expression of methane monooxygenase to alter regioselectivity with aromatic substrates.

FEMS microbiology letters - 6 Jul 2017

Lock Malcolm, Nichol Tim, Murrell J Colin, Smith Thomas J

Abstract excerpt

Soluble methane monooxygenase (sMMO) from methane-oxidising bacteria can oxygenate more than 100 hydrocarbons and is one of the most catalytically versatile biological oxidation catalysts. Expression of recombinant sMMO has to date not been achieved in Escherichia coli and so an alternative expression system must be used to manipulate it genetically. Here we report substantial improvements to the previously...

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Identifiers

PMID: 28854685
DOI: 10.1093/femsle/fnx137
PMCID: PMC5812538

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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