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Article

Rapid Evolution of Primate Type 2 Immune Response Factors Linked to Asthma Susceptibility.

Genome biology and evolution - 1 Jun 2017

Barber Matthew F, Lee Elliott M, Griffin Hayden, Elde Nels C

Abstract excerpt

Host immunity pathways evolve rapidly in response to antagonism by pathogens. Microbial infections can also trigger excessive inflammation that contributes to diverse autoimmune disorders including asthma, lupus, diabetes, and arthritis. Definitive links between immune system evolution and human autoimmune disease remain unclear. Here we provide evidence that several components of the type 2 immune response...

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Identifiers

PMID: 28854632
DOI: 10.1093/gbe/evx120
PMCID: PMC5569703

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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