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Article

The contribution of natural selection to present-day susceptibility to chronic inflammatory and autoimmune disease.

Current opinion in immunology - 1 Dec 2014

Brinkworth Jessica F, Barreiro Luis B

Abstract excerpt

Chronic inflammatory and autoimmune diseases have been the focus of many genome-wide association studies (GWAS) because they represent a significant cause of illness and morbidity, and many are heritable. Almost a decade of GWAS studies suggests that the pathological inflammation associated with these diseases is controlled by a limited number of networked immune system genes. Chronic inflammatory and autoimmune...

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Identifiers

PMID: 25458997
DOI: 10.1016/j.coi.2014.09.008
PMCID: PMC4344185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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