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Article

Expression and Purification of the Pain Receptor TRPV1 for Spectroscopic Analysis.

Scientific reports - 29 Aug 2017

Velisetty Phanindra, Stein Richard A, Sierra-Valdez Francisco J, Vásquez Valeria, Cordero-Morales Julio F

Abstract excerpt

The transient receptor potential vanilloid 1 (TRPV1) channel is an essential component of the cellular mechanism through which noxious stimuli evoke pain. Functional and structural characterizations of TRPV1 shed light on vanilloid activation, yet the mechanisms for temperature and proton gating remain largely unknown. Spectroscopic approaches are needed to understand the mechanisms by which TRPV1 translates...

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Source

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Identifiers

PMID: 28852163
DOI: 10.1038/s41598-017-10426-7
PMCID: PMC5575240

Genes

TRPV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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