Article
[Mg2+]o/[Ca2+]o determines Ca2+ response at fertilization: tuning of adult phenotype?
Reproduction (Cambridge, England) - 1 Nov 2017
Ozil Jean-Pierre, Sainte-Beuve Thierry, Banrezes Bernadette
Abstract excerpt
Alteration of the postnatal phenotype has sparked great concern about the developmental impact of culture media used at fertilization. However, the mechanisms and compounds involved are yet to be determined. Here, we used the Ca2+ responses from mouse eggs fertilized by ICSI as a dynamic and quantitative marker to understand the role of compounds in egg functioning and establish possible correlations with adult...
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