Article
Invisible leashes: The tethering VAPs from infectious diseases to neurodegeneration.
The Journal of biological chemistry - 1 Jan 2000
Dudás Erika F, Huynen Martijn A, Lesk Arthur M, Pastore Annalisa
Abstract excerpt
Intracellular organelles do not, as thought for a long time, act in isolation but are dynamically tethered together by entire machines responsible for interorganelle trafficking and positioning. Among the proteins responsible for tethering is the family of VAMP-associated proteins (VAPs) that appear in all eukaryotes and are localized primarily in the endoplasmic reticulum. The major functional role of VAPs is to...
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