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Article

VPS34 stimulation of p62 phosphorylation for cancer progression

28 Aug 2017

Abstract excerpt

Vps34, a class III PtdIns3 lipid kinase involved in the control of both autophagic and endocytic systems, has been studied extensively in numerous fundamental cellular processes. Accumulating evidence indicates that Vps34 may also contribute to the development and progression of human cancers. However, the mechanism of Vps34 in tumorigenesis remains elusive. Here, we report an unanticipated role of Vps34 in the...

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PMID: 28846113
DOI: 10.1038/onc.2017.295

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