Article

Phosphatidylinositol 4-kinase II β downregulation induces ER stress mediated ROS generation and increases radio-sensitivity in MCF-7

2023-10-03

Abstract excerpt

Type II phosphatidylinositol 4-kinase has historically been associated with vesicular trafficking and growth factor receptor signaling. Recently, it was shown to influence apoptosis, cell adhesion, motility, and inflammatory reactions. Previous study from our group showed that down regulation of PtdIns 4-kinase II β inhibits NF-κB translocation to the nucleus and induce apoptosis in cancer cell lines. Since, NF-κB...

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Literature Corpus work: faa9c3d0-a501-5d10-b965-aef5af90f79e
DOI: 10.1101/2023.10.03.557937

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