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Article

Bile acid receptors in the biliary tree: TGR5 in physiology and disease.

Biochimica et biophysica acta. Molecular basis of disease - 1 Apr 2018

Deutschmann Kathleen, Reich Maria, Klindt Caroline, Dröge Carola, Spomer Lina, Häussinger Dieter, Keitel Verena

Abstract excerpt

Bile salts represent signalling molecules with a variety of endocrine functions. Bile salt effects are mediated by different receptor molecules, comprising ligand-activated nuclear transcription factors as well as G protein-coupled membrane-bound receptors. The farnesoid X receptor (FXR) and the plasma membrane-bound G protein-coupled receptor TGR5 (Gpbar-1) are prototypic bile salt receptors of both classes and...

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Identifiers

PMID: 28844960
DOI: 10.1016/j.bbadis.2017.08.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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