Article
Resistance mechanisms and fitness of Salmonella Typhimurium and Salmonella Enteritidis mutants evolved under selection with ciprofloxacin in vitro.
Scientific reports - 22 Aug 2017
Zhang Chuan-Zhen, Ren Si-Qi, Chang Man-Xia, Chen Pin-Xian, Ding Huan-Zhong, Jiang Hong-Xia
Abstract excerpt
The aim of this study was to investigate the difference in resistance mechanisms and fitness of Salmonella Typhimurium (ST) and Salmonella Enteritidis (SE) mutants selected during the evolution of resistance under exposure to increasing ciprofloxacin concentrations in vitro. Mutations in quinolone target genes were screened by PCR. Phenotypic characterization included susceptibility testing by the broth dilution...
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