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Identification of a short sequence in the HCMV terminase pUL56 essential for interaction with pUL89 subunit

14 Aug 2017

Abstract excerpt

Abstract The human cytomegalovirus (HCMV) terminase complex consists of several components acting together to cleave viral DNA into unit length genomes and translocate them into capsids, a critical process in the production of infectious virions subsequent to DNA replication. Previous studies suggest that the carboxyl-terminal portion of the pUL56 subunit interacts with the pUL89 subunit. However, the specific...

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PMID: 28821882
DOI: 10.1038/s41598-017-09469-7

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