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Article

Accumulation of Deleterious Mutations During Bacterial Range Expansions.

Genetics - 1 Oct 2017

Bosshard Lars, Dupanloup Isabelle, Tenaillon Olivier, Bruggmann Rémy, Ackermann Martin, Peischl Stephan, Excoffier Laurent

Abstract excerpt

Recent theory predicts that the fitness of pioneer populations can decline when species expand their range, due to high rates of genetic drift on wave fronts making selection less efficient at purging deleterious variants. To test these predictions, we studied the fate of mutator bacteria expanding their range for 1650 generations on agar plates. In agreement with theory, we find that growth abilities of strains...

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Identifiers

PMID: 28821588
DOI: 10.1534/genetics.117.300144
PMCID: PMC5629331

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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