Article
Diffusion tensor imaging of brain white matter in Huntington gene mutation individuals.
Arquivos de neuro-psiquiatria - 1 Aug 2017
Saba Roberta Arb, Yared James H, Doring Thomas M, Phys Med, Borges Vanderci, Ferraz Henrique Ballalai
Abstract excerpt
OBJECTIVE: To evaluate the role of the involvement of white matter tracts in huntingtin gene mutation patients as a potential biomarker of the progression of the disease. METHODS: We evaluated 34 participants (11 symptomatic huntingtin gene mutation, 12 presymptomatic huntingtin gene mutation, and 11 controls). We performed brain magnetic resonance imaging to assess white matter integrity using diffusion tensor...
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