Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

No evidence of association between optic neuritis and secondary LHON mtDNA mutations in patients with multiple sclerosis.

Mitochondrion - 1 Sept 2017

Andalib Sasan, Talebi Mahnaz, Sakhinia Ebrahim, Farhoudi Mehdi, Sadeghi-Bazargani Homayoun, Masoudian Nooshin, Vafaee Manouchehr Seyedi, Gjedde Albert

Abstract excerpt

Leber's Hereditary Optic Neuropathy (LHON) shares features with Multiple Sclerosis (MS). Both diseases develop optic lesions. Frequent secondary LHON mutations in MS patients may explain the optic damage. Here, we tested the hypothesis that secondary LHON mutations are associated with optic neuritis (ON) in MS patients. We recruited 56 MS subjects with ON and 47 MS subjects without ON. DNA was extracted by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Genotyping Techniques

Share to Multiple Sclerosis

Share to Optic Atrophy, Hereditary, Leber

Share to Polymorphism, Restriction Fragment Length

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 28802665
DOI: 10.1016/j.mito.2017.08.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

No evidence of association between optic neuritis and secondary LHON mtDNA mutations in patients with multiple sclerosis.PMID 28802665Read ↗

Leber's hereditary optic neuropathy mitochondrial DNA mutations in familial multiple sclerosis.Semantic proximity Read ↗

Leber's hereditary optic neuropathy mutations in Korean patients with multiple sclerosis.Semantic proximity Read ↗

Analysis of the entire mitochondrial genome reveals Leber's hereditary optic neuropathy mitochondrial DNA mutations in an Arab cohort with multiple sclerosis.Semantic proximity Read ↗

Clinical features of MS associated with Leber hereditary optic neuropathy mtDNA mutations.Semantic proximity Read ↗

Secondary mutations of mitochondrial DNA in Japanese patients with Leber's hereditary optic neuropathy.Semantic proximity Read ↗

LHON mutations in Italian patients affected by multiple sclerosis.Semantic proximity Read ↗

Characterization of the mitochondrial genome in childhood multiple sclerosis. II. Multiple sclerosis without optic neuritis and LHON-associated genes.Semantic proximity Read ↗

Screening for Leber's hereditary optic neuropathy associated mitochondrial DNA mutations in patients with prominent optic neuritis.Semantic proximity Read ↗

Mitochondrial abnormalities in patients with LHON-like optic neuropathies.Semantic proximity Read ↗

Characterization of the mitochondrial genome in childhood multiple sclerosis. I. Optic neuritis and LHON mutations.Semantic proximity Read ↗

Leber’s hereditary optic neuropathy and multiple sclerosis: overlap between mitochondrial disease and neuroinflammationSemantic proximity Read ↗

mtDNA haplogroup J: a contributing factor of optic neuritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.