Article
Mitochondrial abnormalities in patients with LHON-like optic neuropathies.
Investigative ophthalmology & visual science - 1 Oct 2006
Abu-Amero Khaled K, Bosley Thomas M
Abstract excerpt
PURPOSE: To investigate certain biochemical and molecular characteristics of mitochondria in patients with Leber hereditary optic neuropathy (LHON)-like optic neuropathies. METHODS: Patients who had LHON-like optic neuropathies in both eyes were selected from neuro-ophthalmology clinics. Evaluation included clinical examination, neuroimaging, and assessment of several mitochondrial parameters in the blood,...
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