Article
HLA-Cw6 in Psoriatic Arthritis: Clinical Phenotype and Therapeutic Impact.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases - 1 Apr 2026
Macia-Villa Cristina, Fernández-Velasco Jose Ignacio, Ferre-Sanfrancisco Mauro, Mendoza-Bravo Daniel Albert, Ruiz-Bejerano Ana Maria, Ferrez-Hernández Celia, Morell-Hita Jose Luis
Abstract excerpt
BACKGROUND: Psoriatic arthritis (PsA) shares genetic features with psoriasis (PsO), with HLA-Cw6 being the main risk allele that may shape its clinical phenotype. This study aimed to evaluate the association between HLA-Cw6 status and clinical features, comorbidities, and treatment outcomes in PsA. METHODS: We conducted a retrospective study of 426 patients with PsA who fulfilled the CASPAR criteria and had...
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