Article
Analytical Strategy to Prioritize Alzheimer's Disease Candidate Genes in Gene Regulatory Networks Using Public Expression Data.
Journal of Alzheimer's disease : JAD - 1 Jan 2017
Kawalia Shweta Bagewadi, Raschka Tamara, Naz Mufassra, de Matos Simoes Ricardo, Senger Philipp, Hofmann-Apitius Martin
Abstract excerpt
Alzheimer's disease (AD) progressively destroys cognitive abilities in the aging population with tremendous effects on memory. Despite recent progress in understanding the underlying mechanisms, high drug attrition rates have put a question mark behind our knowledge about its etiology. Re-evaluation of past studies could help us to elucidate molecular-level details of this disease. Several methods to infer such...
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