Article
Macrophage metabolism in atherosclerosis.
FEBS letters - 1 Oct 2017
Bories Gael F P, Leitinger Norbert
Abstract excerpt
A key aspect of atherosclerosis is the maladaptive inflammatory response to lipoprotein accumulation in the artery. The failure to decrease lipid accumulation, to clear apoptotic cells, and to resolve inflammation ultimately leads to macrophage accumulation within the vascular wall [Thorp EB (2010) Apoptosis15, 1124-1136; Moore K et al. (2013) Nat Rev Immunol 13, 709-721; Moore KJ and Tabas I (2011) Cell 145,...
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